Active ingredient
Nonapeptide-1
A synthetic nonapeptide (9-amino-acid sequence) functioning as an alpha-MSH antagonist; it blocks the melanocyte-stimulating hormone receptor to reduce melanin synthesis, used as a skin-brightening active.
Also known as: melanostatine, melanostatine-5
brighteninganti-pigmentationactive
Benefits
- ✓Inhibits alpha-MSH binding to MC1R receptor to reduce melanin production
- ✓Inhibits tyrosinase for additional anti-pigmentation effect
- ✓Promotes a more even, brighter skin tone
Watch for
- ⚠Considered safe at cosmetic concentrations; no significant cytotoxicity reported
- ⚠Long-term topical safety data is limited compared to established brightening agents
