Active ingredient

Palmitoyl Tripeptide-8

A palmitoylated synthetic tripeptide that mimics the anti-inflammatory signaling domain of alpha-melanocyte-stimulating hormone (α-MSH). Activates melanocortin MC-1R receptors on keratinocytes and immune cells, triggering the same anti-inflammatory cascade as the endogenous neuropeptide. Used in Dr. Jart+ Cicapair formulas and other K-beauty calming products for its potent yet gentle anti-inflammatory and sensitivity-reducing properties.

Also known as: CLIP peptide, tripeptide-8

anti-inflammatoryskin-conditioningsoothing

Benefits

  • Mimic of the body's anti-inflammatory neuropeptide α-MSH — activates MC-1R receptors to downregulate skin inflammation
  • Reduces the release of substance P and other pro-inflammatory cytokines, calming reactive and sensitive skin
  • Palmitoyl chain improves lipid compatibility and skin penetration versus the unmodified peptide

No known watch-fors.

Compatibility

✓ Works well with
+ Niacinamide+ Centella Asiatica Extract+ Allantoin
At a glance
CategoryActive
IrritancyLow
Beginner-friendlyYes
Pregnancy safeYes
In your routine

Pairs well with Niacinamide and Centella Asiatica Extract and others.

Found in 4 products
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Products with Palmitoyl Tripeptide-8

The 6 Peptide Skin Booster SerumSerum
COSRX
The 6 Peptide Skin Booster Serum
A-Amazing Bakuchiol Night CreamMoisturizer
By Wishtrend
A-Amazing Bakuchiol Night Cream
Cicapair Tiger Grass SerumSerum
Dr. Jart+
Cicapair Tiger Grass Serum
Cicapair Tiger Grass Sleepair Intensive MaskMask
Dr. Jart+
Cicapair Tiger Grass Sleepair Intensive Mask