sh-Polypeptide-7 is a recombinant human polypeptide produced by fermentation in E. coli, consisting of a single-chain synthetic fusion peptide identical to an endogenous human growth factor sequence. EU CosIng lists its functions as skin protecting and anti-seborrheic. Based on patent literature and the growth factor complex context in which it appears (alongside sh-Oligopeptide-1 in other formulas), it is likely related to the KGF/FGF-7 (keratinocyte growth factor) family. Used in multi-factor K-beauty anti-aging cream formulas.
skin-protectingskin-conditioninganti-seborrheicanti-aging
✓ Recombinant human polypeptide produced by E. coli fermentation — likely a keratinocyte growth factor (KGF/FGF-7) family member that supports keratinocyte proliferation and skin renewal✓ Skin-protecting and anti-seborrheic activity in the context of a multi-factor growth factor complex, contributing to overall skin balance and barrier integrity✓ Combined with other sh- peptides (sh-Decapeptide-7, sh-Octapeptide-4, sh-Oligopeptide-9) as part of a Caregen-type growth factor cocktail targeting comprehensive skin rejuvenation
⚠ As with all recombinant human growth factors in topical formulations, a theoretical concern exists regarding use by individuals with active skin malignancies; considered safe at cosmetic concentrations for intact healthy skin
+ sh-Decapeptide-7+ sh-Octapeptide-4+ sh-Oligopeptide-9
