Ingredient library

A synthetic sphingolipid analogue developed by Evonik (trade name Ceramide III B analogue), consisting of an isopropanol backbone with two capryloyloxy-palmitamido chains that mimic the structure of ceramide III/NP.

A generic term for ceramide lipids — the primary lipid component of the skin's stratum corneum. When used as an INCI ingredient without a specific number designation, typically indicates a ceramide complex. Essential for skin barrier integrity.

Ceramide AG is the INCI name for Ceramide 6-II, characterized by an alpha-hydroxy fatty acid (A) and dihydrosphingosine (G). One of the naturally occurring ceramides in the stratum corneum. Used in multi-ceramide formulations (Matsuyama Hadauru, Kiku-Masamune, Ishizawa) to restore barrier.

A barrier ceramide that works best alongside other ceramides.

A ceramide class containing an alpha-hydroxy fatty acid bonded to a sphingosine base (alpha-hydroxy fatty acid + sphingosine). Present naturally in the outer layers of human skin and contributes to the intercellular lipid lamellar structure. Typically paired with Ceramide NP, Ceramide AP, and Cholesterol in barrier repair formulations.

A long-chain ceramide important to barrier structure.

A skin-identical ceramide (N-acylated sphinganine; formerly ceramide 2) that reinforces the lamellar lipid barrier to reduce transepidermal water loss and soothe dry, flaking skin.

A skin-identical lipid that rebuilds the barrier.

One of the nine ceramide classes found naturally in human skin (non-hydroxy fatty acid + sphingosine base). Works synergistically with other ceramides and cholesterol to form the intercellular lipid matrix of the stratum corneum. Used in barrier-repair moisturizers alongside Ceramide NP and Ceramide AP.

A synthetic pseudo-ceramide (ceramide analog) developed by Kao (used in Curél) that mimics the structure of natural ceramides to replenish barrier lipids, improve water retention, and soothe dry, atopic skin.

A proprietary ceramide-analogue lipid used in Real Barrier formulations, consisting of a dihydroxyisopropyl backbone with palmoyl-palmamide chains that integrate into the skin's intercellular lipid matrix.

A glycosphingolipid and natural ceramide precursor that the skin converts into active ceramides, progressively reinforcing the stratum corneum lipid barrier.

Glycosphingolipids are sphingolipids with one or more sugar residues. Structural components of the skin's intercellular lipid matrix. Used in Tunemakers' peeling lotion to support barrier function.

A ceramide-analogue from the SKIN-MIMIC technology with lauroyl (C12) chains on a hydroxypropyl-MEA backbone; used alongside Hydroxypropyl Bispalmitamide MEA in Aestura Atobarrier 365 formulations.

A ceramide-like lipid from the SKIN-MIMIC technology combining a hydroxypropyl backbone with two palmitoyl chains and an MEA headgroup, integrating into the skin's intercellular lipid bilayer.

A synthetic ceramide-analogue combining myristoyl/palmitoyl fatty chains with oxostearamide/arachamide MEA, designed to replenish ceramide NP-type lipids in the skin barrier; used in Real Barrier formulations.

A synthetic ceramide analogue — the N-stearoyl amide of dihydrosphingosine. Structurally similar to natural ceramide 2 (Ceramide NS). Directly integrates into the intercellular lipid matrix of the stratum corneum, strengthening the skin barrier. Used in premium Japanese skincare brands.

Sphingoglycolipids (ceramide-like lipids) extracted from rice bran. Structurally similar to skin ceramides, they integrate into the intercellular lipid matrix of the stratum corneum to reinforce the skin barrier. Used in Tunemakers' ceramide essence.