The library

Ingredient library

Every ingredient SkinAtlas knows about — all 2161 of them. What each one does, what it works well with, and what to watch for.

49 ingredients in Barrier support — page 1 of 3

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Barrier support
7-Dehydrocholesterol

A naturally occurring sterol and the direct precursor to vitamin D3 (cholecalciferol) via UVB photolysis. Found in the skin's sebaceous secretions and epidermis. In skincare, applied topically as a barrier-supporting lipid and functional emollient; it behaves similarly to cholesterol in supporting lamellar body structure and skin-barrier integrity. Used in K-beauty formulas targeting compromised or sensitive skin.

emollientskin-conditioningbarrier-support
Provitamin D3 — upon UVB exposure on the skin surface, converts to previtamin D3 and then vitamin D3 (cholecalciferol)Functions similarly to cholesterol as a skin-barrier lipid, intercalating within the stratum corneum lamellar structureSupports epidermal differentiation and barrier integrity analogous to cholesterol supplementation
+ Ceramide NP+ Cholesterol+ Squalane
Barrier support
Arachidic Acid

A C20 saturated fatty acid naturally occurring in peanut oil, fish oils, and skin lipids, used as an emollient and barrier-supportive ingredient in skincare formulations.

emollientbarrier-supportskin-conditioning
Replenishes skin lipids as a long-chain fatty acidContributes to barrier integrity alongside ceramides and cholesterolProvides emollient softening of the skin
May be comedogenic for some skin types at high concentrations
Barrier support
Atractylodes Lancea Root Extract

Extract from the dried rhizome of Atractylodes lancea (Asteraceae), used in TCM as Cangzhu. Principal bioactives are atractylodin (polyacetylene) and sesquiterpenoids β-eudesmol, hinesol, and atractylon, which inhibit 5-LOX and COX-1 inflammatory pathways and support epidermal barrier function. Appears in premium Korean Hanbang formulations paired with other TCM-derived actives for barrier reinforcement and anti-inflammatory benefits.

skin-conditioninganti-inflammatoryantioxidantantimicrobialsoothing
Strengthens the skin's protective barrier, reducing trans-epidermal water loss and improving resilience in stressed or sensitized skinCalms visible redness and inflammatory responses via atractylodin's inhibition of 5-lipoxygenase (5-LOX) and cyclooxygenase-1 (COX-1)Sesquiterpenoids β-eudesmol and hinesol provide antioxidant protection against free radical damage from UV and environmental stress
+ Niacinamide+ Centella Asiatica Extract+ Glycerin
Barrier support
Beta-Sitosterol

A plant sterol (phytosterol) structurally analogous to cholesterol that supports the skin's lipid barrier, reduces inflammation, and soothes sensitive skin.

barrier-supportsoothing
Supports and reinforces the skin barrierSoothes irritation and rednessPlant-derived analogue to skin cholesterol
Barrier support
Bis-Capryloyloxypalmitamido Isopropanol

A synthetic sphingolipid analogue developed by Evonik (trade name Ceramide III B analogue), consisting of an isopropanol backbone with two capryloyloxy-palmitamido chains that mimic the structure of ceramide III/NP.

ceramide-analoguebarrier-repairskin-conditioning
Sphingolipid analogue that integrates into the skin's intercellular lipid matrixSupports barrier recovery in dry or compromised skinClinically studied for atopic-prone skin
Barrier support
Bletilla Striata Root Extract

Bletilla striata (Bai Ji) is a terrestrial orchid native to East Asia whose dried tubers have been used for centuries in Traditional Chinese Medicine to stop bleeding and promote tissue healing. The root extract is valued in premium K-beauty formulations for its high polysaccharide content — primarily glucomannans — delivering both film-forming humectancy and meaningful barrier repair, supported by pharmacological research confirming fibroblast activity stimulation.

barrier-repairwound-healinghumectantsoothing
Rich glucomannan polysaccharides form a moisture-binding film on skin that supports barrier integrity and reduces transepidermal water lossPromotes wound healing and tissue regeneration — well-documented in TCM and supported by in vitro studies showing stimulation of fibroblast proliferation and collagen synthesisMilitarine and phenanthrene compounds contribute anti-inflammatory activity, soothing redness and sensitivity while reinforcing compromised skin barriers
Generally well-tolerated; rare allergy possible in individuals sensitive to orchid-family botanicals
+ Centella Asiatica Extract+ Beta-Glucan+ Sodium Hyaluronate
Barrier support
Brassica Campestris (Rapeseed) Sterol
BRASSICA CAMPESTRIS STEROL

A plant sterol fraction isolated from Brassica campestris (rapeseed/canola). Phytosterols like rapeseed sterol support the skin's lipid bilayer structure and help maintain the integrity of the stratum corneum, making them useful in barrier-repair formulas. Found in 111SKIN Celestial Black Diamond Eye Mask.

emollientbarrier-repairingskin-conditioning
Plant sterol derived from rapeseed (canola) providing structural support to the skin barrier membraneIntegrates into the stratum corneum's lipid lamellar structure alongside ceramides and cholesterol, enhancing barrier integrity
+ Ceramide NP+ Cholesterol
Barrier support
Brassica Campestris (Rapeseed) Sterols
Brassica Campestris Sterols

Phytosterols derived from rapeseed that reinforce the skin's lipid barrier by filling intercellular gaps and reducing transepidermal water loss.

emollientbarrier supportskin conditioning
Strengthens the skin lipid barrierReduces transepidermal water lossImproves hydration
Barrier support
Calcium Phosphoryl Oligosaccharide
CALCIUM PHOSPHORYL OLIGOSACCHARIDES

A proprietary calcium salt of phosphorylated oligosaccharides used in Minon Amino Moist formulas. Clinical studies show it stimulates ceramide production in keratinocytes, reinforcing the skin's moisture barrier — especially beneficial for dry, sensitive, and atopic-prone skin types.

skin-conditioningbarrier-supportingmoisturizing
Supports the skin's natural ceramide synthesisStrengthens the moisture barrierClinically studied for sensitive and atopic-prone skin
+ Ceramide NG+ Glycerin+ Allantoin
Barrier support
Ceramide
CERAMIDE

A generic term for ceramide lipids — the primary lipid component of the skin's stratum corneum. When used as an INCI ingredient without a specific number designation, typically indicates a ceramide complex. Essential for skin barrier integrity.

barrier-supportskin-conditioning
Core component of skin barrier — reduces water lossRestores damaged barrierImproves skin hydration
+ Cholesterol+ Fatty Acids+ Hyaluronic Acid
Barrier support
Ceramide AG
CERAMIDE AG

Ceramide AG is the INCI name for Ceramide 6-II, characterized by an alpha-hydroxy fatty acid (A) and dihydrosphingosine (G). One of the naturally occurring ceramides in the stratum corneum. Used in multi-ceramide formulations (Matsuyama Hadauru, Kiku-Masamune, Ishizawa) to restore barrier.

barrier-supportskin-conditioning
Key skin barrier lipid — reduces transepidermal water lossRestores damaged barrierCeramide 6 (AG) type
+ Ceramide NP+ Ceramide EOP+ Cholesterol
Barrier support
Ceramide AP

A barrier ceramide that works best alongside other ceramides.

ceramide
Restores barrierSupports resilience
+ Ceramide NP+ Cholesterol
Barrier support
Ceramide AS

A ceramide class containing an alpha-hydroxy fatty acid bonded to a sphingosine base (alpha-hydroxy fatty acid + sphingosine). Present naturally in the outer layers of human skin and contributes to the intercellular lipid lamellar structure. Typically paired with Ceramide NP, Ceramide AP, and Cholesterol in barrier repair formulations.

ceramide
Strengthens the skin barrier as one of the naturally present ceramide classes in the stratum corneumSupports moisture retention and reduces water lossComplements Ceramide NP and Ceramide NS in multi-ceramide barrier repair systems
+ Ceramide NP+ Ceramide AP+ Cholesterol
Barrier support
Ceramide EOP

A long-chain ceramide important to barrier structure.

ceramide
Restores barrierLocks in moisture
+ Ceramide NP+ Cholesterol
Barrier support
Ceramide NG

A skin-identical ceramide (N-acylated sphinganine; formerly ceramide 2) that reinforces the lamellar lipid barrier to reduce transepidermal water loss and soothe dry, flaking skin.

ceramidebarrier-support
Replenishes skin barrier ceramidesReduces water loss and restores supplenessImproves dry and flaking skin
Barrier support
Ceramide NP

A skin-identical lipid that rebuilds the barrier.

ceramide
Restores barrierReduces water lossCalms dryness
+ Cholesterol+ Niacinamide
Barrier support
Ceramide NS

One of the nine ceramide classes found naturally in human skin (non-hydroxy fatty acid + sphingosine base). Works synergistically with other ceramides and cholesterol to form the intercellular lipid matrix of the stratum corneum. Used in barrier-repair moisturizers alongside Ceramide NP and Ceramide AP.

ceramide
Restores skin barrier by replenishing a key naturally occurring ceramide classReduces transepidermal water lossSupports barrier resilience alongside Ceramide NP and Ceramide AP
+ Ceramide NP+ Ceramide AP+ Cholesterol
Barrier support
Cetyl-PG Hydroxyethyl Palmitamide

A synthetic pseudo-ceramide (ceramide analog) developed by Kao (used in Curél) that mimics the structure of natural ceramides to replenish barrier lipids, improve water retention, and soothe dry, atopic skin.

ceramidebarrier-supportskin-conditioning
Reinforces the skin barrier by mimicking natural ceramidesImproves water retention in dry and atopic skinClinically studied for atopic dermatitis improvement
Barrier support
Chitosan

Chitosan is a linear polysaccharide derived by partial deacetylation of chitin (found in crustacean shells, insect exoskeletons, and fungal cell walls). The degree of deacetylation determines its cationic charge density — cosmetic-grade chitosan is 75–90% deacetylated. Its cationic nature gives it substantive affinity for skin, excellent film-forming properties, and antimicrobial activity. Used in Korean skincare as a barrier-supportive, skin-conditioning, and gentle anti-microbial active.

film-formingbarrier-repairantimicrobialskin-conditioning
Chitosan is a cationic polysaccharide derived from chitin (crustacean shells) that adsorbs tightly to the negatively charged skin surface, forming a breathable, moisture-retaining film with substantive skin conditioningThe cationic character of chitosan gives it inherent antimicrobial activity against gram-positive bacteria and fungi — relevant for acne-prone and oily skin formulationsLow-molecular-weight chitosan fractions can penetrate into the stratum corneum, reinforcing the lipid barrier and contributing to trans-epidermal water loss reduction
Derived from crustacean shells — not vegan or shellfish-allergy safe; shellfish-allergic individuals should exercise caution, though documented topical reactions are rareHighly cationic — incompatible with anionic polymers (e.g., carbomer, hyaluronic acid at low ionic strength) in formulations; can cause turbidity or precipitation if mixed improperly
+ Panthenol+ Ceramide NP+ Beta-Glucan
× Carbomer
Barrier support
Cholesterol

A key barrier lipid that works synergistically with ceramides.

Supports barrier repairImproves the lipid ratio
+ Ceramide NP
Barrier support
Cholesteryl Hydroxystearate
CHOLESTERYL HYDROXYSTEARATE

A cholesterol ester of hydroxystearic acid that mimics the skin's natural lipid composition. Used in premium Japanese moisturizers to reinforce the stratum corneum barrier and restore hydration.

emollientskin-conditioningbarrier-support
Mimics natural skin lipids to reinforce the barrierRich emollient with barrier-repair propertiesExcellent compatibility with skin's own cholesterol
+ Behenyl Alcohol
Barrier support
Cholesteryl Succinate

The succinate half-ester of cholesterol. Cholesterol is a critical structural component of the skin's lamellar lipid bilayers, maintaining fluidity and barrier integrity. The succinate modification improves water dispersibility compared to free cholesterol, enabling its use in O/W emulsion systems. Commonly included in ceramide-complex formulas alongside Ceramide NP and free fatty acids for a multi-component barrier repair effect.

skin-conditioningemollientbarrier-repair
Cholesterol ester that is more water-dispersible than free cholesterol, allowing it to be incorporated into a wider range of cream and emulsion formatsReplenishes cholesterol — one of the three key lamellar lipids (alongside ceramides and free fatty acids) essential for a healthy skin barrierCholesterol supplementation has been shown in studies to improve barrier recovery speed, particularly in dry or compromised skin
+ Ceramide NP+ Ceramide AP+ Ceramide EOP
Barrier support
Dihydroxyisopropyl Palmoylpalmamide

A proprietary ceramide-analogue lipid used in Real Barrier formulations, consisting of a dihydroxyisopropyl backbone with palmoyl-palmamide chains that integrate into the skin's intercellular lipid matrix.

ceramide-analoguebarrier-repairskin-conditioning
Mimics ceramide structure to replenish intercellular skin lipidsReduces transepidermal water lossSupports barrier recovery in dry and compromised skin
Barrier support
Ectoin

An extremolyte that helps protect skin against environmental stress and supports the barrier.

soothinghumectant
Protects against environmental stressSoothes and hydrates
+ Ceramide NP+ Niacinamide
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