Ingredient library
Every ingredient SkinAtlas knows about — all 2178 of them. What each one does, what it works well with, and what to watch for.
A filtrate from fermented Saccharomyces cerevisiae (brewer's yeast or sake yeast). Contains amino acids, B vitamins, peptides, and fermentation-produced bioactives. Used extensively in Japanese skincare (Elixir, Kiku-Masamune sake line) for skin conditioning and barrier support.
A filtrate of the ferment lysate of Saccharomyces yeast, rich in bioactive amino acids, peptides, vitamins, and organic acids that condition skin and support barrier function.
A filtrate obtained by fermenting barley seed with Saccharomyces yeast, combining beta-glucans and ferulic acid from barley with amino acids and vitamins produced during fermentation, used for skin conditioning and antioxidant benefits.
An extract derived from sardines (Sardina pilchardus), rich in omega-3 fatty acids, amino acids, and peptides. Used in luxury Japanese skincare for its skin-nourishing and antioxidant properties.
Extract from Saussurea involucrata (Snow Lotus), a rare medicinal plant from the Tianshan mountains. Contains unique bioactives including jaceosidin (a flavone) and phenylpropanoids. Featured in premium K-beauty serums as a prestige anti-aging and resilience-boosting botanical.
Extract of creeping saxifrage (Saxifraga sarmentosa/stolonifera), used in skincare for its melanin-inhibiting brightening activity, antioxidant flavonoids, and astringent properties.
An extract derived from smithsonite, a zinc carbonate mineral, providing trace elements used in cosmetics for antioxidant, anti-glycation, and skin-conditioning activity.
The N-acetylated, sodium salt form of sh-oligopeptide-1 (recombinant EGF), a bioengineered epidermal growth factor analogue used to stimulate keratinocyte proliferation, collagen synthesis, and skin renewal.
A stable, water-soluble vitamin C derivative gentle enough for acne-prone skin.
An N-acyl amino acid ester formed from palmitic acid and the amino acid proline. Used in prestige anti-aging formulas for its ability to stimulate matrix proteins and help restore the skin's structural integrity. Commonly formulated as a lipid vesicle complex (e.g. with Nymphaea Alba).
Extract from the root of Sophora flavescens (kushen), a plant used in traditional Chinese and Korean medicine. Contains matrine, oxymatrine, and flavonoids with anti-inflammatory, antioxidant, and anti-aging properties. Used in Elixir Retino Power Cream.
Isoflavone-concentrated extract from soy milk. Contains genistein and daidzein, phytoestrogens with antioxidant properties and evidence for improving skin firmness and tone.
A filtrate obtained by fermenting soybean with lactobacillus or other microorganisms. Fermentation enhances the bioavailability of soy isoflavones and produces beneficial metabolites. Used in Sana's fermented skincare line.
Isoflavone compounds (genistein, daidzein) extracted from soybeans or soymilk. Function as phytoestrogens, binding to estrogen receptors and stimulating collagen synthesis, leading to firmer, more youthful skin. Core active in Sana Namerakahonpo soy products.
An OTC-approved acne-treatment active (up to 10%) that works via antimicrobial and mild keratolytic mechanisms to reduce breakouts and control oil.
Extract from Swertia japonica (Japanese swertia or Japanese gentian). Contains swertiamarin, gentiopicroside, and other iridoid glycosides with soothing and traditional skin-brightening applications.
Lipotec-developed neuropeptide (trade name Leuphasyl) that modulates neurotransmitter release at the neuromuscular junction, reducing muscle micro-contractions that deepen expression wrinkles. Structurally related to enkephalin, a natural pain-modulating peptide.
Tetradecylaminobutyroylvalylaminobutyric Urea Trifluoroacetate (Inyline, Lipotec/BASF) is a long-chain lipopeptide derivative that mimics the acetylcholine receptor-blocking activity of waglerin-1, a peptide from the temple pit viper (Tropidolaemus wagleri). By competitively antagonizing the muscular nicotinic acetylcholine receptor (nAChR), it reduces the force of facial muscle contraction and thereby softens dynamic expression wrinkles. Its mechanism complements SNARE-targeting peptides (e.g., Acetyl Hexapeptide-8) and collagen-stimulating signal peptides, making it a frequent component of comprehensive anti-aging peptide ampoules.
A stable, oil-soluble vitamin C derivative.
Vitamin B1 (thiamine), an essential coenzyme for carbohydrate metabolism; included in cosmetic amino acid and vitamin complex formulas for its skin-conditioning and metabolic support properties.
The hydrochloride salt form of thiamine (vitamin B1), used in cosmetics as a skin-conditioning and antioxidant active; chemically distinct from the free-base Thiamine INCI and provides improved stability and solubility.
A brightening active particularly effective on stubborn pigmentation.
Trifluoroacetyl Tripeptide-2 (sequence TFA-Val-Tyr-Val; trade name Progeline™, Lucas Meyer Cosmetics/IFF; CAS 64577-63-5) is an anti-senescence signal peptide that targets progerin — a truncated lamin A splice variant that accumulates in aging fibroblasts and drives cellular senescence. Reducing progerin slows the molecular aging program while simultaneously inhibiting MMP-1/-3/-9 and elastase, upregulating syndecan-1, and activating the Nrf2 antioxidant pathway. Clinical trials at 4 ppm (8 weeks) showed +20% firmness and +20.9% elasticity with measurable reduction in jawline sagging. Used at extremely low concentrations (0.0004–0.002%) in premium anti-aging serums and ampoules.
POLA's proprietary NEI-L1 compound — a synthetic peptide sodium salt that acts on neuro-expression inhibition pathways to reduce the appearance of expression wrinkles. Used in the Wrinkle Shot Medical Serum N, a Japanese quasi-drug approved for wrinkle treatment.