The library

Ingredient library

Every ingredient SkinAtlas knows about — all 2402 of them. What each one does, what it works well with, and what to watch for.

All 2402 ingredients — page 66 of 101

Emollient
Palmitic Acid

A C16 saturated fatty acid naturally found in skin sebum, used as an emollient and emulsifier to soften skin and stabilize creams.

emollientemulsifier
Softens and conditions skinSupports the skin barrier by replenishing fatty acid content
High concentrations may be moderately comedogenic
Emollient
Palmitic/Stearic Triglycerides

A mixed triglyceride of palmitic (C16) and stearic (C18) fatty acids used as a solid-to-semi-solid emollient that softens skin and improves the texture of balm and cream formulations.

emollientocclusiveskin-conditioning
Softens and conditions skinProvides an occlusive layer to reduce moisture lossRich, smooth texture in balms and creams
Active
Palmitoyl Dipeptide-10

A synthetic signal peptide composed of palmitic acid, alanine, and histidine that provides antioxidant protection, inhibits glycation, and supports skin barrier function with a well-tolerated safety profile.

peptideantioxidantanti-glycation
Neutralizes collagen-degrading enzymesInhibits advanced glycation end-products (AGEs)Supports skin barrier function and moisture retention
Active
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINE

One of the two active peptides in the Syn-Ake complex (Lipotec). Acts at the neuromuscular junction to reduce voluntary muscle contraction, contributing to visibly smoother expression lines over time.

anti-agingskin-conditioning
Mimics Waglerin-1 (temple viper venom peptide) to relax facial muscle micro-contractionsReduces depth of expression linesStudied in combination with its sister peptide for synergistic wrinkle-smoothing
Very low activity at typical use concentrations; meaningful effect requires sustained daily use
+ Palmitoyl Dipeptide-5 Diaminohydroxybutyrate+ Palmitoyl Tripeptide-1+ Niacinamide
Active
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate
PALMITOYL DIPEPTIDE-5 DIAMINOHYDROXYBUTYRATE

The second active component of the Syn-Ake dipeptide complex, working alongside Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine to modulate neuromuscular signaling and soften expression lines.

anti-agingskin-conditioning
Complements Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine in the Syn-Ake complexSupports neuromuscular junction modulation for expression line reduction
Requires consistent use for visible effect
+ Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine+ Palmitoyl Tripeptide-1
Antioxidant
Palmitoyl Grapevine Shoot Extract

A grapevine-derived brightening antioxidant (the 'viniferine' active in Caudalie Vinoperfect), studied for fading hyperpigmentation and dark spots.

antioxidantbrightening
BrightensFades dark spotsAntioxidant protection
+ Niacinamide+ Tocopherol+ Ascorbyl Glucoside
Active
Palmitoyl Heptapeptide-18

A synthetic lipopeptide (palmitic acid conjugated to heptapeptide-18) that binds neurons and inhibits acetylcholine release, producing a topical Botox-like reduction in expression lines.

skin-conditioninganti-agingneuropeptide
Botox-like neuromuscular-relaxing effect that softens expression linesWorks synergistically with Palmitoyl Hexapeptide-52 to potentiate wrinkle-smoothingMay help even skin tone and reduce hyperpigmentation
Active
Palmitoyl Hexapeptide-12

A signal peptide used to support firmness and a smoother, conditioned skin surface.

peptide
Supports firmnessConditioning
+ Matrixyl+ Copper Peptides
Active
Palmitoyl Hexapeptide-52

A synthetic lipopeptide that suppresses neuron-to-muscle signal transfer, providing a topical muscle-relaxing effect that reduces the appearance of expression lines.

skin-conditioninganti-agingneuropeptide
Inhibits acetylcholine release to relax expression-line muscle contractionsPotentiates the effect of Palmitoyl Heptapeptide-18 when combinedImproves the appearance of skin texture, elasticity, and smoothness
Active
Palmitoyl Isoleucine

A lipo-amino acid cosmetic peptide (CAS 54617-29-7) that functions as a plumping and volumizing agent, filling wrinkles and providing anti-aging benefits across all skin layers.

anti-wrinkleplumpingskin protecting
Acts as plumping agent that fills wrinkles and reshapes volumeNatural alternative to lipo-filling with volume and firming effectsAnti-pollution agent with detoxifying properties
Active
Palmitoyl Pentapeptide-4
PALMITOYL PENTAPEPTIDE-4

A palmitoyl-modified pentapeptide (Lys-Thr-Thr-Lys-Ser) known commercially as Matrixyl. Stimulates collagen synthesis and extracellular matrix production, improving skin firmness and reducing wrinkle depth.

anti-agingskin-conditioningcollagen-stimulating
Stimulates collagen I, III, and IV synthesisReduces appearance of wrinkles and fine linesImproves skin firmness and elasticity
+ Adenosine+ Niacinamide+ Ascorbyl Tetraisopalmitate
Active
Palmitoyl Tetrapeptide-10

A signal peptide that promotes skin brightness, accelerates natural exfoliation, and supports tissue regeneration for smoother, more radiant skin.

skin-conditioningcell-communicating
Promotes skin brightness and smoothnessSpeeds up natural skin shedding processSupports tissue regeneration
Active
Palmitoyl Tetrapeptide-7

A signal peptide (part of the Matrixyl 3000 system) that helps reduce inflammatory response and supports collagen production for firmer-looking skin.

anti-agingsoothing
Signals collagenCalms inflammationSupports firmness
+ Palmitoyl Tripeptide-1+ Niacinamide+ Hyaluronic Acid
Active
Palmitoyl Tripeptide-1

A collagen-signalling peptide (the second half of Matrixyl 3000) that prompts skin to rebuild structural proteins, improving firmness over time.

anti-aging
Signals collagenSupports firmnessSmooths fine lines
+ Palmitoyl Tetrapeptide-7+ Hyaluronic Acid
Active
Palmitoyl Tripeptide-38

A signal peptide (Matrixyl Synthe'6) that stimulates endogenous production of collagens, hyaluronic acid, and other matrix components for comprehensive anti-aging benefits.

skin-rejuvenatingcell-communicating
Line-smoothing and plumping properties reduce wrinkle appearanceStimulates collagen, fibronectin, hyaluronic acid, and laminin productionTargets key skin matrix components for improved firmness
Active
Palmitoyl Tripeptide-5

A biomimetic signal peptide of palmitic acid and lysine-valine that stimulates collagen and elastin synthesis through the TGF-beta pathway, improving firmness and reducing the appearance of wrinkles.

peptideanti-agingcollagen-stimulating
Stimulates collagen synthesis via TGF-beta pathwayImproves skin elasticity and firmnessReduces appearance of fine lines and wrinkles
Active
Palmitoyl Tripeptide-8

A palmitoylated synthetic tripeptide that mimics the anti-inflammatory signaling domain of alpha-melanocyte-stimulating hormone (α-MSH). Activates melanocortin MC-1R receptors on keratinocytes and immune cells, triggering the same anti-inflammatory cascade as the endogenous neuropeptide. Used in Dr. Jart+ Cicapair formulas and other K-beauty calming products for its potent yet gentle anti-inflammatory and sensitivity-reducing properties.

anti-inflammatoryskin-conditioningsoothing
Mimic of the body's anti-inflammatory neuropeptide α-MSH — activates MC-1R receptors to downregulate skin inflammationReduces the release of substance P and other pro-inflammatory cytokines, calming reactive and sensitive skinPalmitoyl chain improves lipid compatibility and skin penetration versus the unmodified peptide
+ Niacinamide+ Centella Asiatica Extract+ Allantoin
Antioxidant
Panax Ginseng Berry Extract

An extract from ginseng berries rich in ginsenosides with antioxidant and revitalizing effects.

antioxidantrevitalizing
Antioxidant protectionEnergizes and revitalizes skinImproves radiance
Antioxidant
Panax Ginseng Callus Culture Extract

A biotech-derived extract from cultured ginseng callus cells, providing concentrated ginsenosides and polysaccharides with antioxidant and revitalizing effects without plant harvesting.

antioxidantrevitalizing
Rich in ginsenosides from biofermented cell cultureAntioxidant protection against free radical damageSupports skin revitalization and radiance
Active
Panax Ginseng Extract

An extract from Panax ginseng (unspecified or whole-plant derivation), delivering ginsenosides and polysaccharides for antioxidant and revitalizing skin benefits; distinct from the root-specific INCI Panax Ginseng Root Extract.

antioxidantskin revitalizinganti-aging
Provides ginsenosides with antioxidant and skin-energizing activityBroader ginsenoside profile than root-specific extract when derived from whole or unspecified plant partsSupports skin microcirculation and radiance
Active
Panax Ginseng Flower Extract

Panax Ginseng Flower Extract is derived from the flowers of the ginseng plant, a distinct botanical part with a unique ginsenoside profile compared to the root (the most commonly used part). Flower extracts are enriched in specific saponins and polyphenolic antioxidants that provide skin-brightening and anti-aging benefits. Used in premium Korean beauty products as part of multi-part ginseng complexes (root + flower + seed + berry).

antioxidantskin-brighteningskin-conditioninganti-aging
Ginseng flowers contain a distinct ginsenoside profile enriched in flower-specific saponins (including F1, F2) with potent antioxidant and skin-brightening activity compared to root extractsRich in polyphenols and flavonoids that protect skin from UV-induced oxidative damage and support collagen maintenanceHarvested from the aerial flowering parts of Panax ginseng — a premium, rare ingredient used in high-end Korean skincare alongside root and seed extracts for a full-plant ginseng complex
+ Panax Ginseng Root Extract+ Hydrolyzed Ginseng Saponins+ Niacinamide
Active
Panax Ginseng Leaf/Stem Extract

An extract derived from the leaves and stems (aerial parts) of Panax ginseng, providing a ginsenoside and polyphenol profile distinct from root extracts, with antioxidant and soothing properties.

antioxidantsoothingskin conditioning
Aerial parts (leaf and stem) of ginseng are rich in ginsenosides Rb1, Rd, and Re as well as polyphenolsHigher polyphenol content compared to root extracts in some studiesAntioxidant and mild anti-inflammatory activity
Antioxidant
Panax Ginseng Root Extract

A revered K-beauty botanical used for antioxidant, brightening and revitalizing effects.

brightening
Antioxidant protectionBrightening and revitalizing
+ Niacinamide+ Ascorbic Acid
Active
Panax Ginseng Root Protoplasts

Panax Ginseng Root Protoplasts are plant cell protoplasts — intact ginseng cells with their cellulose cell walls enzymatically removed — derived from Panax ginseng root tissue culture. The protoplast encapsulates the complete intracellular content of the ginseng root cell, including the full ginsenoside profile, polysaccharides, amino acids, enzymes, and cellular organelles, in their natural ratios. Used by Sulwhasoo in their top-tier Timetreasure Honorstige line as a differentiated premium active representing the most complete form of ginseng-derived ingredient delivery.

skin-conditioninganti-agingantioxidantskin-brightening
Plant cell protoplasts of Panax ginseng root — intact ginseng cells with cell walls enzymatically removed — deliver a complete cellular matrix of ginsenosides, polysaccharides, amino acids, and growth-regulatory peptides in their native proportionsThe protoplast format preserves the full range of intracellular ginseng actives (including rare ginsenosides not typically present in aqueous root extracts) for a more comprehensive bioactive deliveryUsed by Sulwhasoo in their ultra-premium Timetreasure line as a signature ingredient representing the pinnacle of their ginseng-derived complex — associated with anti-aging, firming, and skin energy-boosting claims
+ Panax Ginseng Root Extract+ Hydrolyzed Ginseng Saponins+ Panax Ginseng Flower Extract